Cd-17-0745 sequencing of longitudinal biopsies from a patient with nras- mutant melanoma reveals a preexisting pi3kcae545k mutation that increases s6k1 signaling to confer resistance to meki plus cdk4i research articles genomic and functional fidelity of small cell lung cancer patient-derived xenografts. Discover quantitative and qualitative cancer cell line research & explore the publications, figures, data, questions & answers from a vast knowledge base of researchers, including jochen wilhelm explore the latest articles, projects, and questions and answers in cancer cell line, and find cancer cell line experts. Call for papers: emerging biomarkers in oncology research and practice emerging biomarkers in oncology research and practice we are pleased to announce cancer cell international is now accepting submissions for a thematic series on 'emerging biomarkers in oncology research and practice' guest edited by dr aejaz. Basic research paper chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy here we show that in the mouse breast cancer cell lines, 67nr and 4t1, autophagy is induced by the dna damaging agent cisplatin or by drugs that selectively target autophagy regulation, the ptdins3k. Read the latest articles of cancer treatment and research communications at sciencedirectcom, elsevier's leading platform of peer-reviewed scholarly literature. An international journal in cancer research and oncology. Doi: 14343/jcscr20175e1004 research article erythropoietin enhances migration of human neuroblastoma cells: in vitro studies and potential therapeutic implications agata poniewierska-baran, justyna rajewska- majchrzak, and mariusz z ratajczak journal of cancer stem cell research 2017, 5:e1003 (april 27.
So how do we detect these dangerous sleeping cells fortunately, new studies are shedding light on the characteristics of dormant cancer cells for example, our research, in collaboration with the bc cancer agency in canada, has looked at the rna produced by dormant and proliferating cancer cells. Cancer treatment reviews is published by elsevier elsevier articles in press most read most cited ricardo cubedo, virginia martínez, ignacio romero, césar serrano, claudia valverde, javier martín-broto, on behalf of geis (grupo español de investigación en sarcomas/spanish group for sarcoma research. Tumor mutational burden and efficacy of nivolumab monotherapy and in combination with ipilimumab in small-cell lung cancer matthew d hellmann, margaret k callahan, mark m awad, emiliano calvo, paolo a ascierto, akin atmaca, naiyer a rizvi, fred r hirsch, giovanni selvaggi, joseph d szustakowski, ariella. Cancer treatment reviews is published by elsevier articles in press most read most cited of modern concepts and developments in cancer treatment research through the publication of state of the art, authoritative reviews evidence-based reviews (using a priori defined selection process to identify key articles from.
A comprehensive nuclear receptor network for breast cancer cells by kevin white, ralf kittler, sujun hua, chao cheng, mark gerstein in breast cancer, nuclear receptors (nrs) play a prominent role in governing gene expression, have prognostic utility, and are therapeutic targets we built a regulatory map for 24 nrs,. The main active ingredient in turmeric is curcumin or diferuloyl methane, which laboratory studies have shown does have anticancer effects on cancer cells a phase i clinical trial looked at giving curcumin to 25 patients with precancerous changes in different organs this study seemed to show that curcumin could stop the.
Cancer cell publishes peer-reviewed articles reporting major advances in cancer research and oncology, including mechanisms of cancer, therapy resistance, and therapeutic development. Gastrointestinal cancer and stromal tumors, head and neck cancer research, lung cancer diagnosis & treatment, oncology & cancer case reports of lung cancer: targets and therapy, clinical lung cancer, journal of thoracic oncology, the new england journal of medicine, lung cancer journal articles.
Tumor mutational burden and efficacy of nivolumab monotherapy and in combination with ipilimumab in small-cell lung cancer original research article: in press, corrected proof, available online 3 may 2018 matthew d hellmann scott j antonia download pdf. We have recently written another review article on the pros and cons of using lung cancer cells lines ( 1 ) that focuses on the use of cell lines to investigate the hallmarks of cancer ( 2 ) and on the development of in vitro culture systems to study multistage pathogenesis in this review, we focused on the utility of cell lines that. An overview of recent cancer research publications featuring illumina® technology metastasis is a complex process in which cancer cells break away from the primary tumor and circulate through the this paper reports the whole-genome and transcriptome sequencing of tumor and adjacent normal tissue samples. 'amazing, bodywide effects' levy is a pioneer in the field of cancer immunotherapy, in which researchers try to harness the immune system to combat cancer research in his laboratory led to the development of rituximab, one of the first monoclonal antibodies approved for use as an anti-cancer treatment.
The study — which was recently published in the journal nature biomedical engineering — reveals how altering the structure of chromatin in cancer cells could make them easier to destroy in the cell nucleus, dna is wrapped around proteins called histones together they form chromatin chromatin's job.
This article series does not aim for comprehensive coverage of the vast and complex field of cancer cell biology rather, we hope to stimulate our readership with a number of articles highlighting topical and emerging issues in this area of research, and to mark our strong commitment to covering cancer cell. Recent studies, however, have shown that certain types of cells have found a role for lactate last fall, two research articles were the first to provide direct evidence that cancer cells use lactate as fuel to grow and divide remarkably, this basic research finding that improves our understanding of how cancer. Ohsu research team discovers a tumor's 'microenvironment' plays a critical role in how a common type of breast cancer responds to treatment grow,” he said gray and jim korkola, phd, led a team of ohsu researchers to publish a paper in cell systems focused on the area around a tumor, called the. Highlighting advances in cancer research moreover, cancer cell genomes rapidly evolve in response to environmental pressures, a feature that enables the cells to develop drug resistance importantly yevgeniya is a senior editor at science translational medicine, who handles papers in cancer and related topics.